Endocrine Abstracts

Introduction: Extreme insulin resistance monogenic syndromes, including type A insulin resistance syndrome and congenital lipodystrophies, share some phenotypic characteristics with polycystic ovary syndrome (PCOS). These conditions have an increased risk for developing cardiovascular disease and diabetes mellitus. Thus, both an early diagnosis and a personalized management are required at clinical realm.Objective: To assess the prevalence of mutations i...